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Losartan is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. Lowering blood pressure may reduce the risk of strokes and heart attacks.
Specification:
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Items |
Specification |
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Characters |
Description |
White to off-white powder. |
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SOLUBILITY |
FREELY SOLUBLE IN WATER, SLIGHTLY SOLUBLE IN ISOPROPANOL AND IN ACETONITRILE |
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Identification |
(1) infrared absorption spectrophotometry: Corresponds to reference standard |
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(2) ULTRAVIOLET ABSORPTION SPECTROPHOTOMETRY: CORRESPONDS TO THE REFERENCE STANDARD |
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3)TEST FOR POTASSIUM SHOULD BE POSITIVE |
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Water(kf) |
≤0.5% |
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Heavy metals |
≤10ppm |
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Related substances(hplc) |
Individual impurity≤0.2% |
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Total impurity≤0.5% |
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Residual solvents(gc) |
Cyclohexane ≤1000ppm |
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ISOPROPANOL ≤ 2000PPM |
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Assay (hplc) |
98.5%-101.0% Calculated on anhydrous,solvent-free basis |
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Packaging details:
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Packaging details: |
25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum. |
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Storage: |
Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat |
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Shelf Life: |
5 years if sealed and store away from direct sun light. |
