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Tenofovir

  • Product Name : Tenofovir
  • Grade : IP / BP / USP
  • Therapeutic Category : Antiretroviral
  • CAS No : 147127-20-6
  • COA : Available
  • MSDS : Available

Description

 

Tenofovir is a selective antiretroviral agent which functions as a HIV reverse transcriptase inhibitor. Studies indicate that Tenofovir shows a low cytotoxicity in human cell types compared to other nucleoside reverse transcriptase inhibitors.

 

 It is known that HIV replicates its double stranded DNA via reverse transcriptase and then the DNA is integrated into the hosts chromosomes. Tenofovir functions by inhibiting the replication of this DNA. Furthermore, studies suggest that Tenofovir prevents cytoxicity in SIV-infected C- 8166 cells in vitro.

 

Specification:

 

Items Tested

Specification

Result

Characters

White or almost white crystalline powder

Confirms

Assay (HPLC)

99.0~101.0%

Confirms

Melting Point

276~280°C

Confirms

Specific Rotation

-19.3°~-23.7°

Confirms

Loss on drying

Not more than 5.0%

Confirms

Water solubility

13.4mg/mL(25°C)

Confirms

Single Impurity

Not more than 0.2%

Confirms

Total Impurity

Not more than 0.5%

Confirms

Conclusion

Conforms USP32

 

 Packaging details:

 

 

Packaging details:

25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum.

Storage:

Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat

Shelf Life:

5 years if sealed and store away from direct sun light.

Additional Information

The most common markets for this product include the following countries. Please inquire with us if your country or region is not listed:

Asia: Afghanistan, Israel, Jordan, Pakistan, Russia, Saudi Arabia, Singapore, Syria, Philippines, Turkey, Turkmenistan, Uzbekistan, Yemen, Vietnam, Indonesia, Malaysia, Iran, Tajikistan, etc.

Africa: South Africa, Uganda, Nigeria, Ghana, Kenya, Mauritius, Botswana, Egypt, Ethiopia, Libya, Sudan, Congo, Gambia, Ivory Coast , etc.

North & South America: USA, Canada, Panama, Trinidad and Tobago, Costa Rica, Puerto Rico, Dominican Republic, Argentina, Guatemala, Guyana, Peru, Bolivia, Venezuela , Brazil, Bahamas, Ecuador, etc .

Europe: Austria , Azerbaijan, Belarus, Belgium, Cyprus, Czech Republic, Denmark, France, Georgia, Germany, Hungary, Ireland, Iceland, Netherlands, Norway, Poland, Spain, Sweden, Switzerland, Ukraine, United Kingdom (UK) , Latvia, etc.

OCEANIA: Australia, New Zealand, Fiji, etc.

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