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Trimethoprim

  • Product Name : Trimethoprim
  • Grade : IP / BP / USP
  • Therapeutic Category : Folic Acid Antagonist
  • CAS No : 738-70-5
  • COA : Available
  • MSDS : Available

Description

Trimethoprim (INN) is a bacteriostatic antibiotic used mainly in the prophylaxis and treatment of urinary tract infections. It belongs to the class of chemotherapeutic agents known as dihydrofolate reductase inhibitors. Trimethoprim was formerly marketed by GlaxoSmithKline under trade names including Proloprim, Monotrim, and Triprim; but these trade names have been licensed to various generic pharmaceutical manufacturers.

 

Specification:

 

Test  Item

Analysis  Specification

Result

Description

White or yellowish white power

white power

Identification

A Infrared Absorption

B: Ultraviolet Absorption

IR conforms to standard <197k>

Absorptivities, calculated on the dried basis, differ by NMT 3.0%<197u>

Complies

 

complies

 

Melting point

190~203°C

201.5~201.8°C

Loss on drying

≤0.5%

0.1%

Residue on ignition

≤0.1%

0.02%

Chromatographic purity(HPLC)

Individual impurity≤0.1%

Total impurities≤0.2%

0.08%

0.08%

Residual solvents

Methanol  ≤3000 ppm

DMSO   ≤3000 ppm

Complies

Complies

Assay(Dry Basis)

98.5%~101.0%

100.3%

Conclusion

The commodity meets the standard of USP 30.

 

 Packaging details:

 

Packaging details:

25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum.

Storage:

Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat

Shelf Life:

5 years if sealed and store away from direct sun light.

Additional Information

The most common markets for this product include the following countries. Please inquire with us if your country or region is not listed:

Asia: Afghanistan, Israel, Jordan, Pakistan, Russia, Saudi Arabia, Singapore, Syria, Philippines, Turkey, Turkmenistan, Uzbekistan, Yemen, Vietnam, Indonesia, Malaysia, Iran, Tajikistan, etc.

Africa: South Africa, Uganda, Nigeria, Ghana, Kenya, Mauritius, Botswana, Egypt, Ethiopia, Libya, Sudan, Congo, Gambia, Ivory Coast , etc.

North & South America: USA, Canada, Panama, Trinidad and Tobago, Costa Rica, Puerto Rico, Dominican Republic, Argentina, Guatemala, Guyana, Peru, Bolivia, Venezuela , Brazil, Bahamas, Ecuador, etc .

Europe: Austria , Azerbaijan, Belarus, Belgium, Cyprus, Czech Republic, Denmark, France, Georgia, Germany, Hungary, Ireland, Iceland, Netherlands, Norway, Poland, Spain, Sweden, Switzerland, Ukraine, United Kingdom (UK) , Latvia, etc.

OCEANIA: Australia, New Zealand, Fiji, etc.

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