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Citalopram HBr is ramification of Phthalane, a new antidepressant, which has most opposite-selectivity to inhibiting resorption for 5-hydroxytryptamine (5-HT) in congener drugs. Citalopram HBr can inhibit resorption of 5-HT effectively, and is slight to resorption of dopamine and noradrenalin, and is weak or almost none to appetency of alkali-toadstool, histamine and 5-HT acceptor. The drug is all resultful for en-dogenesis and non-endogenesis suffer, and also does not affect heart-conduction system and blood pressure, does not damage surfers' cognizing function and psychomotor, does not enhance inhibiting function resulting from ethanol.
|
Test Items |
Specification |
Results |
|
Description |
White to off white crystalline powder |
Comply |
|
Melting point |
166-170°C |
167.3-168.1°C |
|
Identification |
Positive reaction |
Positive reaction |
|
Related substances |
≤1.0% |
0.16% |
|
Loss on drying |
≤0.5% |
0.06% |
|
Residue on ignition |
≤0.1% |
0.02% |
|
Chloride |
≤0.014% |
<0.014 |
|
Heavy Metals |
≤20ppm |
<20ppm |
|
Clarity of solution |
Conform to standard |
Complies |
|
Microbial Limit |
≤20ppm |
<20ppm |
|
Assay |
≥99.0% |
99.12% |
Packaging details:
|
Packaging details: |
25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum. |
|
Storage: |
Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat |
|
Shelf Life: |
5 years if sealed and store away from direct sun light. |
