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Category

Doxylamine Succinate
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Doxylamine Succinate

  • Product Name : Doxylamine Succinate
  • Grade : IP / BP / USP
  • Therapeutic Category : Antihistamine
  • CAS No : 562-10-7
  • Other Name : Doxylamine
  • COA : Available
  • MSDS : Available

Description

Doxylamine is a first-generation antihistamine. It can be used by itself as a short-term sedative and in combination with other drugs to provide night-time allergy and cold relief. Doxylamine is also used in combination with the analgesics paracetamol (acetaminophen) and codeine as an analgesic/calmative preparation, and is prescribed in combination with vitamin B6 (pyridoxine) to prevent morning sickness in pregnant women.

 

Specification:

 

Test Items

Specifications

Results

Appearance

White or almost white crystalline powder

Conform

Solubility

Very soluble in water, freelysoluble in alcohol

Conform

 

 

 

Identification

1)    Melting range:103℃-108℃

2)    Ultraviolet absorption: UVmax=262.0nm

3)    Organic Nitrogenous Bases

4)    Succinic acid melting range:184℃-188℃

 

105℃

262.0 nm

 

Conform

 

186℃-188℃

Loss on drying

≤0.5%

0.3%

Residue on ignition

≤0.1%

0.1%

Related substances(GC)

Total impurities≤2.0%

Single impurity≤1.0%

1.9%

1.0%

Residual solvents

Diethyl ether≤0.5%

Acetone≤0.5%

Iso-propyl ether≤0.5%

Toluene≤0.1%

0.4%

0.4%

0.4%

0.1%

Assay

98.0%-101.0%

(Calculated on anhydrous substance)

99.2%

 

Packaging details:

 

Packaging details:

25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum.

Storage:

Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat

Shelf Life:

5 years if sealed and store away from direct sun light.

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