Methotrexate was originally developed and continues to be used for chemotherapy, either alone or in combination with other agents. It is effective for the treatment of a number of cancers, including: breast, head and neck, leukemia, lymphoma, lung, osteosarcoma, bladder, and trophoblastic neoplasms.
Specification:
TEST |
SPECIFICATION |
RESULT |
Description |
Yellow crystalline powder |
Conforms |
Identification |
IR,UV conform |
Conforms |
Water |
12.0% Not more than 12.0% |
10.1% |
Residue on ignition |
0.1% Not more than 0.1% |
0.04% |
Chromatographic purity |
Total:Not more than 2.0% |
0.36% |
Specific rotation |
Individual:Not more than 0.5% |
0.26% |
+19°- +24° |
+23.1° |
|
Organic volatile impurities |
Conforms |
Conforms |
Assay |
98.0-102.0% |
99.6% |
Packaging details:
Packaging details: |
25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum. |
Storage: |
Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat |
Shelf Life: |
5 years if sealed and store away from direct sun light. |