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Sulfadoxine is an ultra-long-lasting sulfonamide often used in combination with pyrimethamine to treat or preventmalaria. It is also used, usually in combination with other drugs, to treat or prevent various infections in livestock.
Sulfadoxine competitively inhibits dihydropteroate synthase, interfering with folate synthesis.
Usage:
For skin and soft tissue infection, bronchitis and pneumonia, acute tonsillitis, sore throat, rhinitis, acute bacterium dysentery, urinary tract infections, etc
|
ITEM |
SPECIFICATIONS |
RESULTS |
|
IDENTIFICATION |
A, THE INFRARED ABSORPTION SPECTRUM; B, THE THIN-LAYER CHROMATOGRAPHY; C, THE RESIDUE MELTS AT 80°C TO 82°C OR AT 90°C TO 92°C D, THE REACTION OF PRIMARY AROMATIC AMINES. |
CONFORMS |
|
MELTING POINTS |
ABOUT 198°C, WITH DECOMPOSITION |
197.3~198.4°C |
|
CHARACTERISTICS |
WHITE OR YELLOWISH-WHITE CRYSTALLINE POWDER OR CRYSTALS |
CONFORMS |
|
APPEARANCE OF SOLUBITION |
NOT MORE INTENSELY COLORED THAN Y5, BY5 OR GY5 |
<BY5 |
|
ACIDITY |
NMT 0.2ML |
<0.2ML |
|
RELATED SUBSTANCES |
NMT 0.5% |
<0.5% |
|
HEAVY METALS |
NMT 20PPM |
<20PPM |
|
LOSS ON DRYING |
NMT 0.5% |
0.10% |
|
SULPHATED ASH |
NMT 0.1% |
0.05% |
|
ASSAY (ON DRY BASIS ) |
99.0~101.0% |
99.9% |
|
CONCLUSION: CONFORMS TO THE STANDARD OF BP. |
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Packaging details:
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Packaging details: |
25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum. |
|
Storage: |
Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat |
|
Shelf Life: |
5 years if sealed and store away from direct sun light. |
