Sumatriptan is a medication used for the treatment of migraine and cluster headaches.
It is a synthetic drug belonging to the triptan class. Structurally, it is an analog of the naturally occurring neuro-active alkaloids dimethyltryptamine (DMT), bufotenine, and 5-methoxy-dimethyltryptamine, with an N-methyl sulfonamidomethyl- group at position C-5 on the indole ring.
Specification:
Item |
Specifications |
Character |
Appearance: White or almost white powder. |
Solubility: Freely soluble in water, sparingly soluble in methanol, practically insoluble in methylene chloride. |
|
Identification |
Infrared absorption spectrophotometry: corresponds to Sumatriptan succinate CRS. |
PH |
4.5~5.3 |
Absorbance: |
Maximum 0.10 |
Related substances |
Impurity A: not more than 0.6 percent |
Impurity H: not more than 0.3 percent |
|
Impurity B,C or D: each impurity not more than 0.5 percent |
|
Impurity E or any other impurity: each impurities not more than 0.1 percent |
|
Total impurities: not more than 0.6 percent |
|
Water |
not more than 1.0 percent |
Sulphated ash |
not more than 0.1 percent |
Residual solvents |
Methanol:not more than 3000ppm |
Acetonitrite:not more than 100ppm |
|
Isopropyl Alcohol:not more than 100ppm |
|
Chloroform:not more than 60ppm |
|
Assay |
97.5 percent to102.0 percent (Anhydrous substance). |
Packaging details:
Packaging details: |
25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum. |
Storage: |
Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat |
Shelf Life: |
5 years if sealed and store away from direct sun light. |