Request A Call Back

Category

Travoprost
Inquiry Submitted Successfully

Travoprost

  • Product Name : Travoprost
  • Grade : IP / BP / USP
  • Therapeutic Category : Antiglaucoma
  • CAS No : 157283-68-6
  • COA : Available
  • MSDS : Available

Description

Travoprost ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure. It is a synthetic prostaglandin analog (or more specifically, an analog of prostaglandin F2α) that works by increasing the outflow of aqueous fluid from the eyes.

 

 

Specification:

 

 

Items

Specifications

Results

Appearance

Clear colorless to light yellow oily liquid

Conforms

Solubility

Very souble in acetonitrile and ethanol, practically insoluble in water

Conforms

Identification

TLC: appear as black spots

HPLC: the retention time of the major peak in the chromatogram of assay preparation corresponds to that of the standard preparation as obtained in the assay.

Conforms

Conforms

Optical rotation

+52.0°~+58.0° (anhydrous and solvent free basis)

+53.6°

Water

NMT 1.0%

0.1%

Residual solvents

Ethyl acetate: NMT 0.5%

ND

Related substances

USP travoprost related compound A RS: NMT 0.2%

Epoxide derivative : NMT 0.4%

15-epi Diastereomer: NMT 0.1%

5,6-trans Isomer: NMT 3.5%

15-Keto derivative: NMT 0.3%

Any other individual impurity: NMT 0.1%

Total impurities: NMT 4.0%

ND

0.01%

0.01%

ND

0.01%

ND

0.02%

Assay

96.0%~102.0% (anhydrous and solvent free basis)

98.9%

Conclusion

Conform to Enterprise standard.

 

Packaging details:

 

 

Packaging details:

25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum.

Storage:

Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat

Shelf Life:

5 years if sealed and store away from direct sun light.

×